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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody

PDGFR alpha/CD140a Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241658H4

Cat no : 98141-1-RR

Synonyms

PDGFRA, CD140a antigen, CD140A, CD140 antigen-like family member A, Alpha-type platelet-derived growth factor receptor

Validation Data Gallery

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  • Flow cytometry (FC) experiment of MG-63 cells using Anti-Human PDGFR alpha/CD140a Rabbit Recombinant A (98141-1-RR)

    FC experiment of MG-63 using 98141-1-RR

    1x10^6 MG-63 cells (left) or A-172 cells (right) were surface stained with 0.25 ug Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody (98141-1-RR, Clone: 241658H4) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98141-1-RR

    Affinity and Kinetic Characterization of 98141-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98141-1-RR against Human PDGFR alpha/CD140a were performed. The affinity constant is 2.26 nM.

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Tested Applications

Positive FC detected inMG-63 cells

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98141-1-RR targets PDGFR alpha/CD140a in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant Protein 相同性解析による交差性が予測される生物種
Full Name platelet-derived growth factor receptor, alpha polypeptide
Calculated molecular weight 123 kDa
GenBank accession numberBC015186
Gene symbol PDGFR alpha
Gene ID (NCBI) 5156
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Protocols

Product Specific Protocols
FC protocol for PDGFR alpha/CD140a antibody 98141-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols