PDLIM5 Monoclonal antibody, PBS Only
PDLIM5 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgM
Reactivity
Human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1H9C9
Cat no : 67651-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67651-1-PBS targets PDLIM5 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgM |
Class | Monoclonal |
Type | Antibody |
Immunogen | PDLIM5 fusion protein Ag25059 相同性解析による交差性が予測される生物種 |
Full Name | PDZ and LIM domain 5 |
Calculated molecular weight | 64 kDa |
Observed molecular weight | 63-69 kDa |
GenBank accession number | BC008741 |
Gene symbol | PDLIM5 |
Gene ID (NCBI) | 10611 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Euglobulin precipitation |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PDLIM5 (PDZ and LIM domain 5), formerly known as enigma homolog (ENH), is a cytoplasmic protein containing PDZ domain and LIM domain at N terminus and C terminus, respectively. PDLIM5 gene generates several splicing variants, EZH1 to EZH4. The long isoform, ENH1, is widely expressed in various tissues including heart, brain, spleen, liver and kidney. In comparison, shorter isoforms that lack the LIM motifs are expressed in cardiac (ENH3) and skeletal muscle (ENH2, ENH3, and ENH4). ENH1 is essential for differentiation of striated muscles through interaction with other proteins. In addition, PDLIM5 is also involved in mood disorders, such as schizophrenia, bipolar disorder, and major depression.