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PI3 Kinase p85 Alpha Monoclonal antibody, PBS Only

PI3 Kinase p85 Alpha Monoclonal Antibody for WB, IP, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, pig, rat, rabbit

Applications

WB, IP, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4G3C11

Cat no : 60225-1-PBS

Synonyms

GRB1, p85, p85 ALPHA, PI 3 Kinase p85 alpha, PI 3-kinase p85α, PI3 Kinase p85 Alpha, PI3 kinase subunit p85 alpha, PI3K p85(alpha), PI3K regulatory subunit alpha, PIK3R1



Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

60225-1-PBS targets PI3 Kinase p85 Alpha in WB, IP, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig, rat, rabbit samples.

Tested Reactivity human, mouse, pig, rat, rabbit
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen PI3 Kinase p85 Alpha fusion protein Ag2344 相同性解析による交差性が予測される生物種
Full Name phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Calculated molecular weight 85 kDa
Observed molecular weight 85 kDa
GenBank accession numberBC030815
Gene symbol PIK3R1
Gene ID (NCBI) 5295
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of INS and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.