• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using PQBP1 Recombinant antibody (84491-6-RR)

    WB analysis using 84491-6-RR (same clone as 84491-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84491-6-RR (PQBP1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84491-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using PQBP1 Recombinant antibody (84491-6-RR)

    IF Staining of HeLa using 84491-6-RR (same clone as 84491-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using PQBP1 antibody (84491-6-RR, Clone: 241901B11 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84491-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84491-6-RR

    Affinity and Kinetic Characterization of 84491-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84491-6-RR against Human PQBP1 were performed. The affinity constant is 0.529 nM.

［PR］まずは試したいあなたに。トライアルサイズも特別価格 >>『PRIME BUY抗体特割キャンペーン（4/21～）』

PQBP1 Recombinant antibody, PBS Only

PQBP1 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84491-6-PBS
Clone No.241901B11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

PQBP-1, Polyglutamine-binding protein 1, Polyglutamine tract-binding protein 1, Npw38, 241901B11

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。

国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

84491-6-PBS targets PQBP1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen PQBP1 fusion protein Ag9329 相同性解析による交差性が予測される生物種
Full Name polyglutamine binding protein 1
Calculated molecular weight 265 aa, 30 kDa
Observed molecular weight 30-32 kDa
GenBank accession numberBC012358
Gene Symbol PQBP1
Gene ID (NCBI) 10084
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO60828
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

PQBP1 (Polyglutamine-binding protein 1) is also named as NPW38 and JM26. PQBP1 senses extrinsic tau 3R/4R proteins by direct interaction and triggers an innate immune response by activating a cyclic GMP-AMP synthase (cGAS)-Stimulator of interferon genes (STING) pathway (PMID: 34782623).  PQBP1 is abundantly expressed in the central nervous system during development. PQBP1 is a component of the precatalytic spliceosome (B complex) that is involved in splicing. PQBP1 was predominantly localized in the cell nucleus. PQBP1 is overexpressed in various cancer types including breast cancer, colon cancer, and glioblastoma (PMID: 38342602).