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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite®594-conjugated Plasminogen Monoclonal antibody

Plasminogen Monoclonal Antibody for IF-P

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IF-P

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

1F6A11

Cat no : CL594-66399

Synonyms

Angiostatin, DKFZp779M0222, plasminogen, PLG

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of human liver cancer tissue using CoraLite®594-conjugated Plasminogen Monoclonal ant (CL594-66399)

    IF Staining of human liver cancer using CL594-66399

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®594 Plasminogen antibody (CL594-66399, Clone: 1F6A11 ) at dilution of 1:200.

  • Immunofluorescence (IF) / fluorescent staining of human liver cancer tissue using CoraLite®594-conjugated Plasminogen Monoclonal ant (CL594-66399)

    IF Staining of human liver cancer using CL594-66399

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®594 Plasminogen antibody (CL594-66399, Clone: 1F6A11 ) at dilution of 1:200.

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Tested Applications

Positive IF-P detected inhuman liver cancer tissue

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-66399 targets Plasminogen in IF-P applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Plasminogen fusion protein Ag9938 相同性解析による交差性が予測される生物種
Full Name plasminogen
Calculated molecular weight 810 aa, 91 kDa
Observed molecular weight 105 kDa
GenBank accession numberBC060513
Gene symbol Plasminogen
Gene ID (NCBI) 5340
RRIDAB_2919985
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Plasminogen is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Plasminogen is synthesized in the liver, and it circulates in the blood, with a half-life of 2.2 days. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products (FDP) and D-dimer; the conversion to active protease is mediated by tissue-type (tPA) and urokinase-type (uPA) plasminogen activators. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis.

Protocols

Product Specific Protocols
IF protocol for CL594 Plasminogen antibody CL594-66399Download protocol
Standard Protocols
Click here to view our Standard Protocols