Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
83952-3-PBS targets QSOX1/Quiescin Q6 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | QSOX1/Quiescin Q6 fusion protein Ag3396 相同性解析による交差性が予測される生物種 |
| Full Name | quiescin Q6 sulfhydryl oxidase 1 |
| Calculated molecular weight | 747 aa, 83 kDa |
| Observed molecular weight | 66-83kDa |
| GenBank accession number | BC017692 |
| Gene Symbol | QSOX1 |
| Gene ID (NCBI) | 5768 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | O00391 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
QSOX1(Sulfhydryl oxidase 1) catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.It has two isoforms with the molecular weight of 67 kda and 83 kDa,respectively. It is detected a band of 95 Kda in HT1080 cell lines (PMID:17331072).Isoform 1 is expressed on golgi apparatus membrane and isoform 2 is secreted (PMID:10708601). The isoform1(QSOX1a) is the full length of QSOX1, approximately 78 kd; and the isoform2(QSOX1b) is the splicing form, approximately 62kd(PMID:14633699; 2496424). QSOX1 is highly expressed in tumor cell lines but is not expressed in adjacent normal cells (PMID:21989104).