RAD17 Monoclonal antibody, PBS Only
RAD17 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1F12D8
Cat no : 68539-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
68539-1-PBS targets RAD17 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | RAD17 fusion protein Ag4348 相同性解析による交差性が予測される生物種 |
Full Name | RAD17 homolog (S. pombe) |
Calculated molecular weight | 681 aa, 71 kDa |
Observed molecular weight | 70-80 kDa |
GenBank accession number | BC032304 |
Gene symbol | RAD17 |
Gene ID (NCBI) | 5884 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Rad17, a component of the checkpoint clamp loader complex (RAD17/RFC), was originally initially identified as a DNA damage checkpoint protein. Rad17 participates in cell cycle control and DNA damage repair. Rad17 phosphorylation by ATR (ataxia telangiectasia mutated and Rad3-related) kinase is indispensable for the recruitment of Claspin and the activation of Chk1 in response to genotoxic stress.