☆ 3/31(月)まで!二次抗体 & FlexAbleが30%オフ! >> 免疫アッセイサポートキャンペーン

RASGRF1 Monoclonal antibody, PBS Only

RASGRF1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67010-1-PBS
Clone No.1A4D4

Host / Isotype

Mouse / IgG1

Reactivity

rat, pig

Applications

WB, Indirect ELISA

CDC25, CDC25L, GNRP, GRF1, GRF55, H GRF55, PP13187, Ras GRF1, RAS-GRF, RASGRF1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。


国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67010-1-PBS targets RASGRF1 in WB, Indirect ELISA applications and shows reactivity with rat, pig samples.

Tested Reactivity rat, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen RASGRF1 fusion protein Ag6937 相同性解析による交差性が予測される生物種
Full Name Ras protein-specific guanine nucleotide-releasing factor 1
Calculated molecular weight 134 kDa
Observed molecular weight 145 kDa
GenBank accession numberBC040275
Gene Symbol RASGRF1
Gene ID (NCBI) 5923
RRIDAB_2882327
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ13972
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

RasGRF1, a member of calmodulin-activated guanine-nucleotide exchange factors (GEFs), highly expressed at the synaptic junctions of the central nervous system (CNS). It is similar to the Saccharomyces cerevisiae CDC25. RASGRF1 serves as an in vivo activator for H-RAS and members of the R-RAS and RAC subfamilies. Several studies have shown that RasGRF1 also binds to microtubules and participate in the regulation of neurite outgrowth. RasGRF1 has been implicated in neuronal excitability. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

Loading...