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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67335-1-PBS targets RCC1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse samples.
| Tested Reactivity | Human, mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | RCC1 fusion protein Ag17809 相同性解析による交差性が予測される生物種 |
| Full Name | regulator of chromosome condensation 1 |
| Calculated molecular weight | 421 aa, 45 kDa |
| Observed molecular weight | 45-50 kDa |
| GenBank accession number | BC010067 |
| Gene Symbol | RCC1 |
| Gene ID (NCBI) | 1104 |
| RRID | AB_2882593 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P18754 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation.