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  • Featured Product
  • KD/KO Validated

CoraLite®594-conjugated SERPING1/C1 Inactivator Monoclonal antibody

SERPING1/C1 Inactivator Monoclonal Antibody for IF/ICC

Host / Isotype

Mouse / IgG2a

Reactivity

Human, pig, rat

Applications

IF/ICC

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

1B11B11

Cat no : CL594-66882

Synonyms

C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using CoraLite®594-conjugated SERPING1/C1 Inactivator Mo (CL594-66882)

    IF Staining of HeLa using CL594-66882

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CoraLite®594 SERPING1/C1 Inactivator antibody (CL594-66882, Clone: 1B11B11 ) at dilution of 1:200.

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Tested Applications

Positive IF/ICC detected inHeLa cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-66882 targets SERPING1/C1 Inactivator in IF/ICC applications and shows reactivity with Human, pig, rat samples.

Tested Reactivity Human, pig, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen SERPING1/C1 Inactivator fusion protein Ag16782 相同性解析による交差性が予測される生物種
Full Name serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Calculated molecular weight 500 aa, 55 kDa
Observed molecular weight 100 kDa
GenBank accession numberBC011171
Gene symbol SERPING1
Gene ID (NCBI) 710
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein.

Protocols

Product Specific Protocols
IF protocol for CL594 SERPING1/C1 Inactivator antibody CL594-66882Download protocol
Standard Protocols
Click here to view our Standard Protocols