SIAH1 Recombinant antibody, PBS Only
SIAH1 Recombinant Antibody for WB, IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
240377B4
Cat no : 83389-4-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
The immunogen of 83389-4-PBS is SIAH1 Fusion Protein expressed in E. coli.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | SIAH1 fusion protein Ag34618 相同性解析による交差性が予測される生物種 |
Full Name | seven in absentia homolog 1 (Drosophila) |
Calculated molecular weight | 282 aa, 31 kDa |
Observed molecular weight | 30-34 kDa |
GenBank accession number | BC035562 |
Gene symbol | SIAH1 |
Gene ID (NCBI) | 6477 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
SIAH1, also named as HUMSIAH, Siah-1a and Siah-1S(21kd), belongs to the SINA (Seven in absentia) family. SIAH1 is known to cause indirect degradation of beta-catenin through formation of a complex with Siah-interacting protein (SIP), Skp1 and Ebi. SIAH1 can form heterodimer or homodimer such as Siah-1*Siah-1(70 or 62kd), Siah-1*Siah-1S(42kd) and Siah-1S*Siah-1S(51-56kd). Importantly, results from in vitro soft agar assay demonstrated that Siah-1S displays a promotion effect on cells tumorigenicity. (PMID:17420721)