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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

22815-1-PBS targets SLCO1B3/OATP1B3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SLCO1B3/OATP1B3 fusion protein Ag18940 相同性解析による交差性が予測される生物種
Full Name solute carrier organic anion transporter family, member 1B3
Calculated molecular weight 702 aa, 77 kDa
Observed molecular weight 70-75 kDa
GenBank accession numberBC105597
Gene Symbol SLCO1B3
Gene ID (NCBI) 28234
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NPD5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).

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