SMO Monoclonal antibody, PBS Only
SMO Monoclonal Antibody for IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, Canine
Applications
IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2A11A10
Cat no : 66851-2-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66851-2-PBS targets SMO in IF/ICC, Indirect ELISA applications and shows reactivity with Human, Canine samples.
Tested Reactivity | Human, Canine |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | SMO fusion protein Ag25861 相同性解析による交差性が予測される生物種 |
Full Name | smoothened homolog (Drosophila) |
Calculated molecular weight | 787 aa, 86 kDa |
GenBank accession number | BC009989 |
Gene symbol | SMO |
Gene ID (NCBI) | 6608 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Smoothened (SMO) is a G protein-coupled receptor that is a component of the hedgehog (Hh) signaling pathway and is conserved from flies to humans. The Hh pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. Expressed on the primary cilium, SMO interacts with the patched protein, a receptor for Hh proteins.