CoraLite® Plus 488-conjugated TACSTD2/TROP2 Monoclonal antibody
TACSTD2/TROP2 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
5A6B1
Cat no : CL488-68141
Synonyms
Validation Data Gallery
Tested Applications
| Positive IF/ICC detected in | HaCaT cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL488-68141 targets TACSTD2/TROP2 in IF/ICC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | TACSTD2/TROP2 fusion protein Ag25775 相同性解析による交差性が予測される生物種 |
| Full Name | tumor-associated calcium signal transducer 2 |
| Calculated molecular weight | 36 kDa |
| Observed molecular weight | 40-50 kDa |
| GenBank accession number | BC009409 |
| Gene symbol | TROP2 |
| Gene ID (NCBI) | 4070 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 TACSTD2/TROP2 antibody CL488-68141 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
