Validation Data Gallery
Tested Applications
Positive FC detected in | Balb/c mouse peritoneal macrophages |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
98018-1-RR targets TLR4/CD284 in FC applications and shows reactivity with mouse samples.
Tested Reactivity | mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | TLR4/CD284 fusion protein Ag32998 相同性解析による交差性が予測される生物種 |
Full Name | toll-like receptor 4 |
Calculated molecular weight | 96 kDa |
GenBank accession number | NM_021297 |
Gene Symbol | Tlr4 |
Gene ID (NCBI) | 21898 |
RRID | AB_3672162 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9QUK6 |
Storage Buffer | PBS with 0.09% sodium azide. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
Background Information
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Protocols
Product Specific Protocols | |
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FC protocol for TLR4/CD284 antibody 98018-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |