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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

TMEM184B Polyclonal antibody, PBS Only

TMEM184B Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28031-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of mouse brain tissue using TMEM184B Polyclonal antibody (28031-1-AP)

    IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using TMEM184B Polyclonal antibody (28031-1-AP)

    IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using TMEM184B Polyclonal antibody (28031-1-AP)

    IHC staining of mouse cerebellum using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using TMEM184B Polyclonal antibody (28031-1-AP)

    IHC staining of mouse cerebellum using 28031-1-AP (same clone as 28031-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

28031-1-PBS targets TMEM184B in IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TMEM184B fusion protein Ag27704 相同性解析による交差性が予測される生物種
Full Name transmembrane protein 184B
GenBank accession numberBC015489
Gene symbol TMEM184B
Gene ID (NCBI) 25829
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Transmembrane protein 184B (TMEM184B) is a seven-pass transmembrane protein highly expressed in the nervous system and is thought to play a role in neuronal excitability, synaptic structure, and expression of key developmental and adult pathways involved in neuronal differentiation (PMID: 27122027; 37730546). TMEM184B may activate the MAP kinase signaling pathway (PMID: 12761501). TMEM184B has also been reported to be necessary for interleukin-31-induced itch, promoting adult somatosensation through developmental Wnt signaling and promotion of proper pruriceptive gene expression (PMID: 34629389).