- Featured Product
- KD/KO Validated
4-1BBL/TNFSF9 Monoclonal antibody
4-1BBL/TNFSF9 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
1B4B1
Cat no : 66450-1-Ig
Synonyms
Validation Data Gallery
Filter:
Tested Applications
| Positive WB detected in | Raji cells, Ramos cells, Daudi cells, K-562 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 2 publications below |
| WB | See 3 publications below |
| IHC | See 2 publications below |
| IF | See 1 publications below |
Product Information
66450-1-Ig targets 4-1BBL/TNFSF9 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | 4-1BBL/TNFSF9 fusion protein Ag12768 相同性解析による交差性が予測される生物種 |
| Full Name | tumor necrosis factor (ligand) superfamily, member 9 |
| Calculated molecular weight | 254 aa, 27 kDa |
| Observed molecular weight | 27 kDa |
| GenBank accession number | BC104805 |
| Gene symbol | TNFSF9 |
| Gene ID (NCBI) | 8744 |
| RRID | AB_2881819 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TNFSF9, also named as 4-1BBL, belongs to the tumor necrosis factor family. It is a cytokine that binds to TNFRSF9. TNSF9 induces the proliferation of activated peripheral blood T-cells. It may have a role in activation-induced cell death (AICD) and may play a role in cognate interactions between T-cells and B-cells/macrophages.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for 4-1BBL/TNFSF9 antibody 66450-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Aging (Albany NY) TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
| ||
Int Immunopharmacol TNFSF9 promotes metastasis of pancreatic cancer by regulating M2 polarization of macrophages through Src/FAK/p-Akt/IL-1β signaling
| ||
BMC Cancer Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis | ||
Hepatol Commun HBV infection effects prognosis and activates the immune response in intrahepatic cholangiocarcinoma |
