CoraLite® Plus 488-conjugated TRIM2 Monoclonal antibody
TRIM2 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse, Rat, Pig
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1H9C2
Cat no : CL488-67342
Synonyms
Validation Data Gallery
Tested Applications
Positive IF-P detected in | mouse brain tissue |
Recommended dilution
Application | Dilution |
---|---|
Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL488-67342 targets TRIM2 in IF-P applications and shows reactivity with Human, Mouse, Rat, Pig samples.
Tested Reactivity | Human, Mouse, Rat, Pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TRIM2 fusion protein Ag14637 相同性解析による交差性が予測される生物種 |
Full Name | tripartite motif-containing 2 |
Calculated molecular weight | 744 aa, 82 kDa |
Observed molecular weight | 70-85 kDa |
GenBank accession number | BC011052 |
Gene symbol | TRIM2 |
Gene ID (NCBI) | 23321 |
RRID | AB_2919456 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Tripartite motif-containing 2(TRIM2) is an E3 ubiquitin ligase which directs proteasome-mediated degradation of target proteins by the ubiquitination of NEFL and phosphorylation of BCL2L11. This protein contains an N-terminal RING domain, followed by a B-box-2 domain, a coiled-coil region, and 6 C-terminal NHL repeats. TRIM2 involves in the apoptotic response to ischemia via directing degradation of BIM protein, thus has a role in neuroprotection.
Protocols
Product Specific Protocols | |
---|---|
IF protocol for CL Plus 488 TRIM2 antibody CL488-67342 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |