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TRPV1 Monoclonal antibody

TRPV1 Monoclonal Antibody for WB, ELISA
Cat No. 66983-1-Ig
Clone No.1A3C9

Host / Isotype

Mouse / IgG1

Reactivity

Human and More (2)

Applications

WB, CoIP, ELISA

Capsaicin receptor, DKFZp434K0220, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inHepG2 cells, MDA-MB-468 cells, T-47D cells, HEK-293 cells, Y79 cells, HUVEC cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66983-1-Ig targets TRPV1 in WB, CoIP, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman, sheep
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TRPV1 fusion protein Ag18683 相同性解析による交差性が予測される生物種
Full Name transient receptor potential cation channel, subfamily V, member 1
Calculated molecular weight 839 aa, 95 kDa
Observed molecular weight 105 kDa
GenBank accession numberBC132820
Gene Symbol TRPV1
Gene ID (NCBI) 7442
RRIDAB_2882302
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8NER1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRPV1, also named as VR1 or OTRPC1, belongs to the transient receptor potential (TRP) family and TRPV subfamily (PMID: 17579562). TRPV1 is a ligand-activated non-selective calcium permeant cation channel expressed predominantly by sensory neurons (PMID: 10821274). It is involved in detection of noxious chemical and thermal stimuli. TRPV1 plays an important role in inflammatory thermal hyperalgesia (PMID: 10764638; 10821274).

Protocols

Product Specific Protocols
WB protocol for TRPV1 antibody 66983-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

Int J Mol Sci

The Contribution of TSLP Activation to Hyperalgesia in Dorsal Root Ganglia Neurons of a Rat.

Authors - Chun-Ching Lu
WB

Biochim Biophys Acta Mol Basis Dis

Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway

Authors - ShuoQi Li
humanWB

EBioMedicine

Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis

Authors - Zhongyang Lv
humanWB

Int J Mol Sci

Luteolin Alleviates Oxidative Stress in Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke via Modulation of the TRPV1 and CYP2A13/NRF2 Signaling Pathways

Authors - Lina Zhou
humanWB

Front Mol Biosci

Role of TRPV1 ion channel in cervical squamous cell carcinoma genesis

Authors - Zhenming Wang
humanWB

J Inflamm Res

Cannabidiol Inhibits Inflammation Induced by Cutibacterium acnes-Derived Extracellular Vesicles via Activation of CB2 Receptor in Keratinocytes

Authors - Ziqi Jiang
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