Validation Data Gallery
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Tested Applications
| Positive IF-P detected in | mouse lung tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL488-10490 targets Uteroglobin/CC10 in IF-P applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Uteroglobin/CC10 fusion protein Ag0758 相同性解析による交差性が予測される生物種 |
| Full Name | secretoglobin, family 1A, member 1 (uteroglobin) |
| Calculated molecular weight | 10 kDa |
| GenBank accession number | BC004481 |
| Gene Symbol | Uteroglobin |
| Gene ID (NCBI) | 7356 |
| RRID | AB_3083880 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P11684 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Uteroglobin, also known as CC10, is a member of the secretoglobin family of small secreted proteins. It is produced by the nonciliated, nonmucous, secretory epithelial clara cells of the pulmonary airways, was first identified in lung lavage by Singh and colleagues. It has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 Uteroglobin/CC10 antibody CL488-10490 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |