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CoraLite® Plus 488-conjugated XIAP Monoclonal antibody
XIAP Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2A1A12
Cat no : CL488-66800
Synonyms
Validation Data Gallery
Tested Applications
Positive IF-P detected in | human colon cancer tissue |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL488-66800 targets XIAP in IF-P applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | XIAP fusion protein Ag18088 相同性解析による交差性が予測される生物種 |
Full Name | X-linked inhibitor of apoptosis |
Calculated molecular weight | 60 kDa |
GenBank accession number | BC032729 |
Gene symbol | XIAP |
Gene ID (NCBI) | 331 |
RRID | AB_2919373 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells.
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 XIAP antibody CL488-66800 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |