Validation Data Gallery
Filter:
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
11888-1-PBS targets XLF in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | XLF fusion protein Ag2496 相同性解析による交差性が予測される生物種 |
| Full Name | nonhomologous end-joining factor 1 |
| Calculated molecular weight | 35 kDa |
| Observed molecular weight | 33-38 kDa |
| GenBank accession number | BC030986 |
| Gene Symbol | XLF |
| Gene ID (NCBI) | 79840 |
| RRID | AB_2282851 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H9Q4 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
XRCC4-like factor (XLF), also known as Cernunnos and NHEJ1, is a protein encoded by the human NHEJ1 gene and an important repair factor for DNA double-strand breaks. NHEJ is a well-known mechanism for the repair of double-strand breaks (DSBs), a lethal type of DNA damage in mammalian cells. It basically utilizes a group of enzymes to take hold of the ends of a broken DNA molecule, create a bridge between them, and subsequently re-ligate the broken DNA molecule.