• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Validation Data Gallery

Filter:
  • Immunohistochemistry (IHC) staining of mouse brain tissue using Biotin-conjugated tPA Polyclonal antibody (Biotin-10147)

    IHC staining of mouse brain using Biotin-10147

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using Biotin-10147 (tPA antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of mouse brain tissue using Biotin-conjugated tPA Polyclonal antibody (Biotin-10147)

    IHC staining of mouse brain using Biotin-10147

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using Biotin-10147 (tPA antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human kidney tissue using Biotin-conjugated tPA Polyclonal antibody (Biotin-10147)

    IHC staining of human kidney using Biotin-10147

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using Biotin-10147 (tPA antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human kidney tissue using Biotin-conjugated tPA Polyclonal antibody (Biotin-10147)

    IHC staining of human kidney using Biotin-10147

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using Biotin-10147 (tPA antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

［PR］まずは試したいあなたに。トライアルサイズも特別価格 >>『PRIME BUY抗体特割キャンペーン（4/21～）』

  • Featured Product
  • KD/KO Validated

Biotin-conjugated t-Plasminogen activator/tPA Polyclonal antibody

t-Plasminogen activator/tPA Polyclonal Antibody for IHC
Cat No. Biotin-10147

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC

Synonyms

PLAT, tPA, T PA, Reteplase, EC:3.4.21.68

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Biotin
Size/Concentration: 

-/ -

ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。

国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive IHC detected inmouse brain tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

Biotin-10147 targets t-Plasminogen activator/tPA in IHC applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen t-Plasminogen activator/tPA fusion protein Ag0200 相同性解析による交差性が予測される生物種
Full Name plasminogen activator, tissue
Calculated molecular weight 57 kDa
Observed molecular weight 32-35 kDa, 65 kDa
GenBank accession numberBC002795
Gene Symbol tPA
Gene ID (NCBI) 5327
RRIDAB_2934328
Conjugate Biotin
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP00750
Storage Buffer PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Plasminogen activator, tissue (PLAT, synonyms: TPA, T-PA) is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein (33 kDa and 32 kDa). PLAT enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. tPA has 4 isoforms produced by alternative splicing with the MW of 63 kDa, 33 kDa, 57 kDa and 44 kDa.

Protocols

Product Specific Protocols
IHC protocol for Biotin t-Plasminogen activator/tPA antibody Biotin-10147Download protocol
Standard Protocols
Click here to view our Standard Protocols