ARL13B Monoclonal antibody, PBS Only
ARL13B Monoclonal Antibody for WB, IF/ICC, IF-Fro, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse, pig, canine
Applications
WB, IF/ICC, IF-Fro, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1H6C3
Cat no : 66739-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66739-1-PBS targets ARL13B in WB, IF/ICC, IF-Fro, Indirect ELISA applications and shows reactivity with human, mouse, pig, canine samples.
Tested Reactivity | human, mouse, pig, canine |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | ARL13B fusion protein Ag12031 相同性解析による交差性が予測される生物種 |
Full Name | ADP-ribosylation factor-like 13B |
Calculated molecular weight | 48 kDa |
Observed molecular weight | 60 kDa |
GenBank accession number | BC094725 |
Gene symbol | ARL13B |
Gene ID (NCBI) | 200894 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).