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  • Featured Product
  • KD/KO Validated

CoraLite®594-conjugated ASGR1 Polyclonal antibody

ASGR1 Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

Cat no : CL594-11739

Synonyms

ASGP R 1, ASGPR, ASGPR 1, ASGR1, asialoglycoprotein receptor 1, CLEC4H1, Hepatic lectin H1, HL 1, Hs.12056

Validation Data Gallery

Applications:
  • IF Staining of rat liver using CL594-11739

    IF Staining of rat liver using CL594-11739

    Immunofluorescent analysis of (4% PFA) fixed rat liver tissue using CoraLite®594 ASGR1 antibody (CL594-11739) at dilution of 1:200.

  • IF Staining of rat liver using CL594-11739

    IF Staining of rat liver using CL594-11739

    Immunofluorescent analysis of (4% PFA) fixed rat liver tissue using CoraLite®594 ASGR1 antibody (CL594-11739) at dilution of 1:200.

  • IF Staining of human liver cancer using CL594-11739

    IF Staining of human liver cancer using CL594-11739

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®594 ASGR1 antibody (CL594-11739) at dilution of 1:200.

  • IF Staining of human liver cancer using CL594-11739

    IF Staining of human liver cancer using CL594-11739

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®594 ASGR1 antibody (CL594-11739) at dilution of 1:200.

Tested Applications

Positive IF detected inrat liver tissue, human liver cancer tissue
Planning an IHC experiment? We recommend our IHCeasy ASGR1 Ready-To-Use IHC Kit. ASGR1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 11739-1-AP

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL594-11739 targets ASGR1 in IF applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ASGR1 fusion protein Ag2310 相同性解析による交差性が予測される生物種
Full Name asialoglycoprotein receptor 1
Calculated molecular weight 291 aa, 33 kDa
GenBank accession numberBC032130
Gene symbol ASGR1
Gene ID (NCBI) 432
RRIDAB_2919773
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.

Protocols

Product Specific Protocols
IF protocol for CL594 ASGR1 antibody CL594-11739Download protocol
Standard Protocols
Click here to view our Standard Protocols