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C1qC Monoclonal antibody

C1qC Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 66268-1-Ig
Clone No.1C5B4

Host / Isotype

Mouse / IgM

Reactivity

human and More (1)

Applications

WB, IF/ICC, ELISA

C1Q C, C1qC, C1QG

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
CoraLite® Plus 488
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inhuman plasma tissue
Positive IF/ICC detected inHUVEC cells

Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunofluorescence (IF)/ICCIF/ICC : 1:400-1:1600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66268-1-Ig targets C1qC in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, rat
Host / Isotype Mouse / IgM
Class Monoclonal
Type Antibody
Immunogen C1qC fusion protein Ag10233 相同性解析による交差性が予測される生物種
Full Name complement component 1, q subcomponent, C chain
Calculated molecular weight 245 aa, 26 kDa
Observed molecular weight 26 kDa
GenBank accession numberBC009016
Gene Symbol C1QC
Gene ID (NCBI) 714
RRIDAB_2881653
Conjugate Unconjugated
Form Liquid
Purification MethodThiophilic affinity chromatograph
UNIPROT IDP02747
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1qC which is the C-chain polypeptide of human complement subcomponent C1q.

Protocols

Product Specific Protocols
WB protocol for C1qC antibody 66268-1-IgDownload protocol
IF protocol for C1qC antibody 66268-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Sci Rep

C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.

Authors - Anika Alberts
ratWB

J Ethnopharmacol

Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu Decoction against ischemic stroke.

Authors - Lingyu Pan
humanWB

Onco Targets Ther

Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma.

Authors - Hanji Huang
humanIF

PLoS Genet

Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer

Authors - Tiantian Ji
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