Anti-Mouse CD103 (2E7)
CD103 Monoclonal Antibody for FC
Host / Isotype
Hamster / IgG
Reactivity
Mouse and More (1)
Applications
IF, FC
Conjugate
Unconjugated
CloneNo.
2E7
Cat no : 65047-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | mouse splenocytes |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
IF | See 2 publications below |
FC | See 1 publications below |
Product Information
65047-1-Ig targets CD103 in IF, FC applications and shows reactivity with Mouse samples.
Tested Reactivity | Mouse |
Cited Reactivity | mouse |
Host / Isotype | Hamster / IgG |
Class | Monoclonal |
Type | Antibody |
Immunogen | C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) 相同性解析による交差性が予測される生物種 |
Full Name | integrin alpha E, epithelial-associated |
GenBank accession number | BC150690 |
Gene symbol | CD103 |
Gene ID (NCBI) | 16407 |
RRID | AB_2918359 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | PBS with 0.09% sodium azide. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
Background Information
CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).
Protocols
Product Specific Protocols | |
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FC protocol for CD103 antibody 65047-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Biomolecules Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice | ||
J Nanobiotechnology Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair | ||
Biomed Pharmacother Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice |