CoraLite® Plus 647 Anti-Mouse CD103 (2E7)
CD103 Monoclonal Antibody for FC
Host / Isotype
Hamster / IgG
Reactivity
Mouse
Applications
FC
Conjugate
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
2E7
Cat no : CL647-65047
Synonyms
Validation Data Gallery
Tested Applications
| Positive FC detected in | mouse splenocytes |
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL647-65047 targets CD103 in FC applications and shows reactivity with Mouse samples.
| Tested Reactivity | Mouse |
| Host / Isotype | Hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) 相同性解析による交差性が予測される生物種 |
| Full Name | integrin alpha E, epithelial-associated |
| GenBank accession number | BC150690 |
| Gene symbol | CD103 |
| Gene ID (NCBI) | 16407 |
| RRID | AB_2883652 |
| Conjugate | CoraLite® Plus 647 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 654 nm / 674 nm |
| Form | Liquid |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 647 CD103 antibody CL647-65047 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
