CoraLite® Plus 405 Anti-Rat CD11b (OX42)
CD11b Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG2a, kappa
Reactivity
Rat
Applications
FC
Conjugate
CoraLite® Plus 405 Fluorescent Dye
CloneNo.
OX42
Cat no : CL405-65229
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | Wistar rat splenocytes |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL405-65229 targets CD11b in FC applications and shows reactivity with Rat samples.
Tested Reactivity | Rat |
Host / Isotype | Mouse / IgG2a, kappa |
Class | Monoclonal |
Type | Antibody |
Immunogen | Rat peritoneal macrophages 相同性解析による交差性が予測される生物種 |
Full Name | integrin alpha M |
Calculated molecular weight | 127 kDa |
GenBank accession number | NM_012711 |
Gene symbol | CD11b |
Gene ID (NCBI) | 25021 |
Conjugate | CoraLite® Plus 405 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 399 nm / 422 nm |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | PBS with 0.09% sodium azide. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
Protocols
Product Specific Protocols | |
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FC protocol for CL Plus 405 CD11b antibody CL405-65229 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |