FITC Plus Anti-Rat CD11b (OX42)

CD11b Monoclonal Antibody for FC

Host / Isotype

Mouse / IgG2a, kappa

Reactivity

rat and More (1)

Applications

FC

Conjugate

FITC Plus Fluorescent Dye

CloneNo.

OX42

Cat no : FITC-65229

Synonyms

OX42, Itgam, integrin alpha M


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Tested Applications

Positive FC detected inrat bone marrow cells

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

FCSee 3 publications below

Product Information

FITC-65229 targets CD11b in FC applications and shows reactivity with rat samples.

Tested Reactivity rat
Cited Reactivitymouse, rat
Host / Isotype Mouse / IgG2a, kappa
Class Monoclonal
Type Antibody
Immunogen Rat peritoneal macrophages 相同性解析による交差性が予測される生物種
Full Name integrin alpha M
Calculated molecular weight127 kDa
GenBank accession numberNM_012711
Gene symbol CD11b
Gene ID (NCBI) 25021
Conjugate FITC Plus Fluorescent Dye
Excitation/Emission maxima wavelengths495 nm / 524 nm
Form Liquid
Purification MethodAffinity purification
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

Protocols

Product Specific Protocols
FC protocol for FITC Plus CD11b antibody FITC-65229Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratFC

Mol Med Rep

Discovery of microglia gonadotropin‑releasing hormone receptor and its potential role in polycystic ovarian syndrome

Authors - Fan Wang
ratFC

Biomater Res

CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial Homeostasis

Authors - Pengcheng Tu
mouseFC

Heliyon

Peimine promotes microglial polarization to the M2 phenotype to attenuate drug-resistant epilepsy through suppressing the TLR4/NF-κB/HIF-1α signaling pathway in a rat model and in BV-2 microglia

Authors - Chongchong Liu