PE Anti-Mouse CD31 (390)
CD31 Monoclonal Antibody for FC
Host / Isotype
Rat / IgG2a, kappa
Reactivity
mouse
Applications
FC
Conjugate
PE Fluorescent Dye
CloneNo.
390
Cat no : PE-65058
Synonyms
Validation Data Gallery
Tested Applications
| Positive FC detected in | mouse bone marrow cells |
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
PE-65058 targets CD31 in FC applications and shows reactivity with mouse samples.
| Tested Reactivity | mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | C3H/HeJ mouse hematopoietic progenitor cell line 32D 相同性解析による交差性が予測される生物種 |
| Full Name | platelet/endothelial cell adhesion molecule 1 |
| GenBank accession number | BC008519 |
| Gene symbol | CD31 |
| Gene ID (NCBI) | 18613 |
| RRID | AB_2883855 |
| Conjugate | PE Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 496 nm, 565 nm / 578 nm |
| Form | Liquid |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for PE CD31 antibody PE-65058 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
