• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated CHMP7 Polyclonal antibody

CHMP7 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-16424

Synonyms

Chromatin-modifying protein 7, Chromatin modifying protein 7

Validation Data Gallery

Filter:
  • Immunofluorescence (IF) / fluorescent staining of A431 cells using CoraLite® Plus 488-conjugated CHMP7 Polyclonal ant (CL488-16424)

    IF Staining of A431 using CL488-16424

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using CoraLite® Plus 488 CHMP7 antibody (CL488-16424) at dilution of 1:200.

☆大好評トライアルサイズ ¥20,000～！ >>> 一次抗体特別価格キャンペーン開催中！

Tested Applications

Positive IF/ICC detected inA431 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-16424 targets CHMP7 in IF/ICC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CHMP7 fusion protein Ag9625 相同性解析による交差性が予測される生物種
Full Name CHMP family, member 7
Calculated molecular weight 453 aa, 51 kDa
Observed molecular weight 51-55 kDa
GenBank accession numberBC019110
Gene symbol CHMP7
Gene ID (NCBI) 91782
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CHMP7 (Charged multivesicular body protein 7), it is expected to be located in the nucleus and cytoplasm, which is ubiquitinated in lymph node and appendix. It is reported that Lem2p (LEM2), a member of the LEM (Lap2- Emerin-Man1) family of inner nuclear membrane proteins, and the ESCRT-II/ESCRT- III hybrid protein Cmp7p (CHMP7), work together to recruit additional ESCRT-III proteins to holes in the nuclear membrane. CHMP7 protein is involved in several processes, including late endosome to vacuole transport; midbody abscission; and mitotic nuclear division. It is a part of ESCRT III complex, which colocalizes with chromatin. The molecular weight of CHMP7 is 50 kDa.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 CHMP7 antibody CL488-16424Download protocol
Standard Protocols
Click here to view our Standard Protocols