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CoraLite®594-conjugated COX2/ Cyclooxygenase 2/ PTGS2 Monoclonal antibody
COX2/ Cyclooxygenase 2/ PTGS2 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
IF-P
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
3G2B9
Cat no : CL594-66351
Synonyms
Validation Data Gallery
Tested Applications
Positive IF-P detected in | mouse lung tissue |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL594-66351 targets COX2/ Cyclooxygenase 2/ PTGS2 in IF-P applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | COX2/ Cyclooxygenase 2/ PTGS2 fusion protein Ag24721 相同性解析による交差性が予測される生物種 |
Full Name | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
Calculated molecular weight | 604 aa, 68 kDa |
Observed molecular weight | 66-70 kDa |
GenBank accession number | BC013734 |
Gene symbol | COX2/PTGS2 |
Gene ID (NCBI) | 5743 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
COX2 (Prostaglandin G/H synthase 2, PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72-74 kDa and the aglycosylated is 66 kDa (PMID:19656660). It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276).
Protocols
Product Specific Protocols | |
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IF protocol for CL594 COX2/ Cyclooxygenase 2/ PTGS2 antibody CL594-66351 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |