CoraLite® Plus 405 Anti-Human CTLA-4/CD152 Rabbit Recombinant Antibody

CTLA-4/CD152 Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

CoraLite® Plus 405 Fluorescent Dye

CloneNo.

240793E8

Cat no : CL405-98078

Synonyms

CTLA4, Cytotoxic T-lymphocyte protein 4, CTLA 4, CELIAC3, CD152


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Tested Applications

Positive FC detected inPHA treated human PBMCs

Recommended dilution

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

Product Information

CL405-98078 targets CTLA-4/CD152 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name cytotoxic T-lymphocyte-associated protein 4
Calculated molecular weight 223 aa, 25 kDa
GenBank accession numberBC070162
Gene symbol CTLA4
Gene ID (NCBI) 1493
Conjugate CoraLite® Plus 405 Fluorescent Dye
Excitation/Emission maxima wavelengths399 nm / 422 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses.

Protocols

Product Specific Protocols
FC protocol for CL Plus 405 CTLA-4/CD152 antibody CL405-98078Download protocol
Standard Protocols
Click here to view our Standard Protocols