CoraLite® Plus 405 Anti-Human CTLA-4/CD152 Rabbit Recombinant Antibody
CTLA-4/CD152 Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
FC
Conjugate
CoraLite® Plus 405 Fluorescent Dye
CloneNo.
240793E8
Cat no : CL405-98078
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | PHA treated human PBMCs |
Recommended dilution
Application | Dilution |
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This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL405-98078 targets CTLA-4/CD152 in FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Recombinant protein 相同性解析による交差性が予測される生物種 |
Full Name | cytotoxic T-lymphocyte-associated protein 4 |
Calculated molecular weight | 223 aa, 25 kDa |
GenBank accession number | BC070162 |
Gene symbol | CTLA4 |
Gene ID (NCBI) | 1493 |
Conjugate | CoraLite® Plus 405 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 399 nm / 422 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses.
Protocols
Product Specific Protocols | |
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FC protocol for CL Plus 405 CTLA-4/CD152 antibody CL405-98078 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |