CoraLite® Plus 488-conjugated RIAM,APBB1IP Monoclonal antibody
RIAM,APBB1IP Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG2a
Reactivity
Human, Mouse
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2F8A2
Cat no : CL488-67143
Synonyms
Validation Data Gallery
Tested Applications
Positive IF/ICC detected in | Jurkat cells |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL488-67143 targets RIAM,APBB1IP in IF/ICC applications and shows reactivity with Human, Mouse samples.
Tested Reactivity | Human, Mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | RIAM,APBB1IP fusion protein Ag4602 相同性解析による交差性が予測される生物種 |
Full Name | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
Calculated molecular weight | 666 aa, 73 kDa |
Observed molecular weight | 100 kDa |
GenBank accession number | BC035636 |
Gene symbol | RIAM |
Gene ID (NCBI) | 54518 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
APBB1IP gene encodes a Rap1-GTP-interacting adapter molecule (RIAM) which is an important protein in Rap1-mediated integrin activation and adhesion. Rap1 is a small GTPase frequently activated in tumors such as melanoma and prostate cancer. RIAM is widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes. RIAM may function in the signal transduction from Ras activation to actin cytoskeletal remodeling. The observed molecular weight of RIAM is about 100 kDa.
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 RIAM,APBB1IP antibody CL488-67143 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |