CoraLite® Plus 488-conjugated Serpin C1/Antithrombin III Monoclonal antibody
Serpin C1/Antithrombin III Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2B2E5
Cat no : CL488-66052
Synonyms
Validation Data Gallery
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Tested Applications
| Positive IF/ICC detected in | HepG2 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL488-66052 targets Serpin C1/Antithrombin III in IF/ICC applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Serpin C1/Antithrombin III fusion protein Ag9880 相同性解析による交差性が予測される生物種 |
| Full Name | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
| Calculated molecular weight | 464 aa, 53 kDa |
| Observed molecular weight | 53 kDa |
| GenBank accession number | BC022309 |
| Gene symbol | Serpin C1/Antithrombin III |
| Gene ID (NCBI) | 462 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 Serpin C1/Antithrombin III antibody CL488-66052 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
