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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite® Plus 488-conjugated ZMPSTE24 Recombinant antibody

ZMPSTE24 Recombinant Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

241288C3

Cat no : CL488-84547-2

Synonyms

FACE-1, FACE1, FACE 1, EC:3.4.24.84, CAAX prenyl protease 1 homolog

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of PC-3 cells using CoraLite® Plus 488-conjugated ZMPSTE24 Recombinant (CL488-84547-2)

    IF Staining of PC-3 using CL488-84547-2

    Immunofluorescent analysis of (4% PFA) fixed PC-3 cells using CoraLite® Plus 488 ZMPSTE24 antibody (CL488-84547-2, Clone: 241288C3 ) at dilution of 1:200.

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Tested Applications

Positive IF/ICC detected inPC-3 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-84547-2 targets ZMPSTE24 in IF/ICC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ZMPSTE24 fusion protein Ag33613 相同性解析による交差性が予測される生物種
Full Name zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Calculated molecular weight 475 aa, 55 kDa
GenBank accession numberBC037283
Gene symbol ZMPSTE24
Gene ID (NCBI) 10269
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189).

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 ZMPSTE24 antibody CL488-84547-2Download protocol
Standard Protocols
Click here to view our Standard Protocols